Essay, Research Paper: Sickle Cell Anemia

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The problem is that sickle cell anemia affects about 72,000 Americans in the
United States. Sickle cell anemia is an inherited disease in which the body is
unable to produce normal hemoglobin, an iron-containing protein. Abnormal
hemoglobin can morph cells that can become lodged in narrow blood vessels,
blocking oxygen from reaching organs and tissues. The effects of sickle cell
anemia are bouts of extreme pain, infectious, fever, jaundice, stroke, slow
growth, organ, and failure. Sickle cell anemia hurts many people today in fact
it hurts about 72,000 Americans. But some doctors are finding cures for this
inherited disease. This disease causes mainly strokes and fever. With this
disease a stroke is not predictable, a stroke can happen as early as a one month
old as a baby. It can hurt a person really bad because it causes them to not be
able to do many things like can't play sports, and things that gets your heart
pumping because if the red blood cells gets clogged up it can causes a stroke
because oxygen can't flow. Most Americans who have sickle cell anemia are of
African descent. The disease also affects Americans from the Caribbean, Central
America, and parts of South America, Turkey, Greece, Italy, the Middle East and
East India. Since sickle cell anemia is an inherited disease if both parents
have the trait for sickle cell, their baby's chances of having sickle cell
disease is one in four. Many doctors are trying to find cures for this disease
by trying the solution on patients. Doctors at Emory University and University
of Mississippi Medical Center in Jackson, Chicago. Doctors in Emory University
in Atlanta credited an experimental stem cell transplant that for the first time
is not from a related donor. This transplant cured the inherited disease from
Keone Penn who is 13 years old from Georgia. He suffered a stroke at 5 years old
and had a fever of 106 degrees, "I almost died" (Ferraro, Newspaper
Article) What the doctors did was replaced the boy's bone marrow with stem cells
taken from the umbilical cord blood of an infant not related to him. Dr. Ruby
Bellevue of New York Methodist Hospital in Brooklyn has patient that he wants to
do the transplant procedure on, but he is waiting for more studies to come out
to see what the long-term effects are. Some effects could be rejection,
complications, and/or death. For many years, doctors could only treat the sickle
cell disease with blood transfusions and antibiotics. But until now, the only
hope for a cure has been through bone marrow transplants, dangerous and rarely
performed because they require a match between donor and the person receiving
it. The good thing about stem cell transplants is does not require as precise a
match. For Keone the 13 years old kid was worth it. "I am happy. This has
been my wish my whole life, to not have sickle cell." (Ferraro, Newspaper
Article) The doctors of University of Mississippi Medical Center use Doppler
ultrasound to examine head and neck blood flow. The ultrasound measures the
speed of the blood in the vessels. Early detection can help and decrease the
risk of stroke. The program involved in this problem is the National Institutes
of Health declared September as Sickle Cell Awareness Month. The educational and
research organization have promoted awareness of sickle cell disease, a group of
inherited disorders characterized by anemia which means a reduced number of red
blood cell and the production of sickle hemoglobin is a molecule found in red
blood cells that carries oxygen from the lungs to other parts of the body. My
suggestion for dealing with this problem is to go to the doctor to get an
examination if you play any sports or go for a jog or run and experiment any
difficulty breathing. If you don't have trouble breathing, maybe if you feel
dizzy or feel like you about to blackout when you do something I recommend going
to the doctors for an examination. It is better to find out the problem first
before you will experiment a stroke a high fever that can cause a death. I think
early detection help a lot and could save your life. You could find out your
parents medical background or file since sickle cell anemia is an inherited
disease. This problem which sickle cell anemia is important because it affects
72,000 Americans and one of every 500 African-American is born with the disease
and one in every 1,000 to 1,400 Hispanics. People can die from this disease, and
many kids died at a young age. I think in the future doctors will find a cure
with no side effects or long-term effects. Right now the have a temporary cure
for this disease. I really hope they will find a cure for this disease that
really works.

Bibliography
Brown, David "Sickle Cell Anemia", Washington Post, 1993 Ferraro,
Susan "Sickle Cell Miracle", Daily News, 1999 Oyo, Remi
"Encouraging Signs in Research on Sickle Cell", Inter Press Service,
July 25,1997 Starr, Cindy "Sickle Cell Anemia", The Cincinnati Post,
1998 Ultrasound Identifies Stroke Risk In Sickle Cell Patients, December 24,1999

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